The NTCP p.Ser267Phe Variant Is Associated With a Faster Anti-HBV Effect on First-Line Nucleos(t)ide Analog Treatment

iphone 14 pro max price miami Sodium taurocholate cotransporting polypeptide (NTCP) acts as a cellular receptor for the hepatitis B virus infection of host hepatocytes.Previously, many studies confirmed that the NTCP p.Ser267Phe variant was a protective factor against HBV-related disease progression.We therefore designed this study to investigate w

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Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines

The NR2F2 gene encodes the transcription factor COUP-TFII, which is upregulated in embryonic mesoderm.Heterozygous variants in NR2F2 cause a spectrum of congenital anomalies including cardiac and gonadal phenotypes.We generated heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2-knockout induced pluripotent garmin 67 stem cell (iPSC) li

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Reduced nicotine content cigarettes in smokers of low socioeconomic status: study protocol for a randomized control trial

Abstract Background The Family Smoking Prevention and Tobacco Control Act gave the Food and Drug Administration jurisdiction over the regulation of all tobacco products, including their nicotine content.Under this act, a major strategy to reduce harm from cigarette tobacco is lowering the nicotine content without causing unintended adverse conseque

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Transitioning a Marquee Orientation and Transition Program for Increased New Student Engagement and Retention Amidst the COVID-19 Pandemic

One mid-sized public flagship institution in the Mountain West was forced to abandon le boudoir de luna cognac a brand-new marquee orientation and transition program, which had contributed to the first increase in first-time student retention numbers in a decade.As educators around the world were faced with similar challenges, three main concerns a

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